(CC) Top 200 Drugs Chapter 3 Respiratory Nursing Pharmacology by Suffix (Memorizing Pharmacology)
09
October

By Adem Lewis / in , , , , , , , , , , , , /


This is Chapter three respiratory or
respiratory and I’m going to do the same thing just for efficiency sake I’ve
already written everything up on the board so that I’m just going to
highlight stems. I’m going to highlight drug classes drug classifications and in
the order in which I put them the first section we’re going talk about are
antihistamines and you’re dividing it to histamines in first and second
generation there’s controversy over whether there’s a third generation drugs
like fexofenadine which is Allegra is one that might be in the third
generation a third generation drug would be something that’s maybe a metabolite
or one of the isomers of the racemic mixture so I’m not going to go into a
third generation, first and second is enough for just our purposes right now
so antihistamines H-1 first generation is diphenhydramine and again we have this
non-alphabetical order so I put an ABC with a slash and then ABC with an arrow
here to explain why so we begin with first-generation diphenhydramine.
Diphenhydramine is in that generation that was first invented and these made
people very drowsy you can see B E and D in benadryl so you can think of bed and
you can also see the D R Y because it’s drying helps with allergy symptoms
okay but diphenhydramine that’s first generation that goes through the
blood-brain barrier makes them on drowsy second generation on the other cetirizine and loratadine so [brands] Zyrtec and Claritin these don’t cause the
drowsiness because they can’t get through the blood-brain barrier or they
can’t stay through the blood-brain barrier and loratadine has a stem it’s
-atadine and I know spelling has been de-emphasized since I was a kid so
I’m a gen X-er I was clapping erasers and had chalkboards and things like that but
in drug name spelling is incredibly important because you pronounce
loratadine the same as you pronounce famotidine
and the ta-da ine and the actual stem is -atadine sounds just like the -tidine
in the H-2 blockers but if you spell it -tidine by accident you’ve just made
this drug instead of for allergies for acid and we don’t want to do that so
paying attention to spelling is very important with these medications. So cetirizine, [brand] Zyrtec this -tir- in cetirizine is pronounced “tear” so you can think
of tearing from allergy eyes. Loratadine has the -atadine stem and the Claritin Clear commercials have been very clear about what it’s for
you see people outside having fun on the picnic you even look at the box it’s
blue sky so Claritin Clear for allergies but what I want to talk about also is
this loratadine-D so what is that D? Well D is for decongestant and that
decongestant is pseudoephedrine so pseudoephedrine is brand name Sudafed
and you’ll see it as loratadine-D or Claritin-D and what’s the rationale for
that well if you have allergies and nasal congestion if you just use
loratadine or claritin it’s not going to help
but if use loratadine with a decongestant then it will take care of
the allergy symptoms and the congestion. This decongestant
pseudoephedrine where Sudafed is actually BTC it’s behind the counter
you have to show ID for it this -rin or -drin I think is the is the stem and because it’s behind the counter there’s
a certain amount that any person can get in a single day certain amount you can
get in a month because the pseudoephedrine can be used to make
methamphetamine or meth but one of my students said I’m so fed up with being
congested and that’s how you remember pseudoephedrine or sudafed so what we’re
doing to remember these is we start over-the-counter with these
antihistamines in this decongestant and what we’re going to do is we’re going to
go into the nose so we’re physically thinking okay we’re in the nose now
and phenylephrine is the PE in many oral liquids
and it’s very similar to pseudoephedrine except this one is not regulated you can
get as much of it as you want the brand name for the nose one is Neo-Synephrine
and then another one which can be used in the nose another decongestant is
oxymetazoline which is Afrin and this nasal spray you should really only use
for three days otherwise you might get some kind of rebound congestion so we’re
staying in the nose and that’s how we’re just like in the in the GI chapter we
went from stomach down to intestines we’re staying in the nose and then we’ll
go down to the chest so we have triamcinolone and this -lone
some people use as a way to remember that it’s a steroid, it’s not a proper
stem. The brand name, the ‘-cort’ stands for cortical steroid and nasa- for nose again
it’s not a stem you can’t have a stem in a brand name but these are hints
that let you know what it’s for but allergic rhinitis you have an -itis that
means you have an inflammation so informations we can use some kind of
steroid so for the first group here we’re starting with anti-histamines then
we go to the decongestant then allergic rhinitis and we’re being very mindful of
where we are in the body. So we’re going to go from the nose to then cough
which is going to be in the chest so just as we’ve done before we’re going to
go from an OTC to a prescription and this is where we make our jump.
Everything before just now is over-the-counter behind the counter. So
guaifenesin is a mucolytic and some people get that confused because they’ve
seen robitussin for coughs so long but the guaifenesin is actually just m-u-c-o-l-y-t-i-c a mucolytic is something that breaks up mucus or breaks up chest
congestion the stem is in dextromethorphan but you may never see
that word you might just see the DM okay so guaifenasin with
dextromethorphan is Robitussin DM there’s also Mucinex DM either one of
those but the -orphan stem is the one that
tells you it’s dextromethorphan if the cough doesn’t subsist and maybe you go to
the prescriber and say you know I’ve had this cough for a week and it’s just not
going away it’s not productive they might prescribe something like
codeine now in the United States codeine you can’t just get it over the counter
you used to be able to get a little bit but now it’s regulated and that Cheratussin the ‘cher’ is for cherry and then AC some people just use anti cough but I
think and codeine was probably what it stood for okay and then -tussin an
antitussive is something that’s for cough. So if that cough doesn’t go
away and you still have that chest congestion if the prescriber is being very
aggressive maybe they’ll treat the inflammation in the chest and they’ll do
that with a steroid with either methylprednisolone or prednisone and
again we’re staying with our alphabetical within the class of
steroids and methylprednisolone this is an infix so in English we can have
something that’s a prefix before we can have a suffix which is at the end or we
can have an infix and in fixes are extremely rare in English but they’re
not rare when it comes to medications so the -pred- not the -lone is what tells
you it’s a prednisone type steroid but some people still use that -lone or -sone
as their cue but really the stem is that -pred- so maybe we go from the
chest and we stay in the chest and stay in the lungs and in the lungs we’re
going to talk about these asthmatic medications and so we have budesonide
and we pronounce this -son- not as sun but as sone and I’m not going to
underline it because it’s not a proper stem but some people still use it to
recognize this is the steroid part and I put fluticasone this -sone underneath it
because these two drugs are doing the same thing they’re long-acting steroids
that are going to be inhaled so we have the steroid part of it for asthma and
then we also have what’s, I put beta-2 here a beta-2 agonist is a bronchodilator it’s
going to open up your lungs and the stem for that is -terol. t-e-r-o-l. t-e-r-o-l. You’re
probably most familiar with albuterol but in these long-acting versions formoterol and budesonide come together to make symbicort so they’re symbiotic
together working together with a corticosteroid and then fluticasone is
working together with salmeterol to give you air or you’re adding them
together spelling add ad instead of a DD to get air fluticasone can you can find
it alone and what I did was where these are combination medicines I just
staggered this I put a hanging indent where the fluticasone is on this side
under the steroids and albuterol is on this side just to show you that I’m just
separating this out where these are long-acting these are sure this is
long-acting but this is a little bit more short acting so if fluticasone
comes as Flonase for the nose but also it’s Flovent if you’re going to use it
orally and then this albuterol is that rescue inhaler that most people are
familiar with what I did here was I put prophylaxis before acute so our
healthcare system is really treat once you’ve something’s happened but ideally
you don’t get asthma attacks because you take these long-acting medications but
sometimes you might have a breakthrough asthma attack and you would want that
rescue inhaler the beta-2 agonist albuterol so I kept with that alignment
so albuterol the -terol is under here and another combination product but here we
have -tropium and -tropium is an anticholinergic the -chol c-h-o-l is
about acetylcholine and acetylcholine is a neurotransmitter we’re talking about
ipratropium does a really good job with asthma as well and this comes in the
medication DuoNeb literally two, a duo that can be nebulized and so albuterol works as a bronchodilator ipratropium as well and
they work in concert together tiotropium also has this -tropium stem to let you
know there’s an anticholinergic but this one is a little bit more long-acting
than this short acting one and tiotropium is a long-acting
anticholinergic and this brand name is Spiriva and if you think of the word
respire or respiration you see the s-p-i-r and there but it’s the -tropium stems that lets you know this is an anticholinergic medication so again now
we’ve gone from then just using some of the cognitive tools to go from
over-the-counter to Rx we’re going from a cough which is in the chest to the
lungs which is in the chest and asthma and then we’re going to go on from these
medications to three other medications that can be used in asthma incidents and
things like that the leukotriene inhibitor montelukast
the stem -lukast seems an awful lot like leukotriene it’s given once a day and
that’s where that single comes from in Singular and then if you’re asthmatic
and it’s helping your condition then the air a-i-r is what helps. Anti IgE antibody
so again one of these biologics omalizumab so the -mab tells you it’s a
monoclonal antibody and then -li- and -zu- also have meaning I won’t go into it
here but it’s in the book and it’s important to understand what the
biologics we’re going to have these complex stems telling us where it’s from
and that’s Xolair and that to me that just sounds like extra air so again a
way to remember that it’s for it asthma but this is an injectable the one thing
with omalizumab is that it can cause anaphylaxis so you always have to have
somebody around when it’s being injected an epinephrine or an EpiPen is what you
would use okay so epi means above neph means kidney so above the kidney what’s
above the kidney the adrenal gland so epinephrine is an injectable that
does something very similar to the adrenal gland which is secrete epinephrine there’s another word it’s also called that’s very similar and I’ll just
put it here it’s called adrenaline and this is the Latin version so ad- means
above or to towards and then -renal- means kidney and then so this is the Roman or
the Latin and then this is the epinephrine is the Greek but that’s the
respiratory medications in a nutshell


13 thoughts on “(CC) Top 200 Drugs Chapter 3 Respiratory Nursing Pharmacology by Suffix (Memorizing Pharmacology)

  1. Thank you for this upload! I was not pronouncing Budesonide/Fomorterol, Fluticasone/Salmeterol, and Montelukast (as well as the word Leukotriene) correctly. I know you mentioned there are a couple ways to pronounce Omalizumab, but you said it the way I was saying it! I've found that learning these drugs is a lot easier when I have confidence in pronouncing them correctly. I also appreciated the clarification that Phenylephrine is P.E. on the labels because I was wondering why the OTC Sudafed had the active ingredient of Phenylephrine instead of Pseudoephedrine and why it was on the shelves in the first place instead of BTC.

  2. For phenylephrine, you state it is the P.E. in many oral liquids. Could you please define what P.E. stands for? Thank you.

  3. This was insanely simple and clear, and I loved the mnemonics! Saving my behind on tomorrow's Respiratory Test.

  4. guafenesin is a cough expectorant not a mucolytic.mucolytics include ambroxol,bromohexine,acetylcysteine.

  5. Do you have a good idea of how to add information such as: indications, dosage, route, contraindications, side effects etc.? Once I get these drugs memorized I will need to add that information to my knowledge.

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