Dr. Mark Hyman | Talks at Google

By Adem Lewis / in , , , , , , /

[applause]>>Liv Wu: Hi, everyone. [applause]>>Liv Wu: Hi, everyone. I’m Liv Wu, Executive
Chef, and I’m excited and delighted that Mark Hyman accepted our invitation to speak to
us as part of our Optimize Your Life, Health Speaker Series. I first met Mark at a health conference and
was struck by-by this man’s extraordinary level of enthusiasm and energy. He talks fast.
And-and how just passionate he is about health and well being. He tells a compelling story about finding
and living in ways that optimizes all our systems and-and-and drive us to perform well
and feel well and thrive. I don’t think I’ll ever encounter the word
“ultra” again without thinking of-of Mark. He’s kind of the ultra guy. [laughter] The gains, the greatest gains in 90% of medicine
and longevity have been about cleaning up; cleaning up the inner and outer environment.
And in the early 20th century it was about clean water, basic sanitation, getting rid
of infections. And so now at the dawn of the 21st century
we need to look at cleaning up again. From processed, highly refined, chemicalized foods
we consume to the air we breathe, and-and all the other toxicities that are, that are
part of our world. Mark combines his training in conventional
medicine with cutting edge genetics and nutrition, and tells us why and how we should clean up
within and without so that we can really perform as ultra human beings. Mark is a four-time New York Times best-selling
author and Chairman of the Institute for Functional Medicine which is a very exciting new field;
a real paradigm shift in-in medicine. He has dedicated his career to identifying
and addressing the root causes of chronic illness through a groundbreaking whole systems
approach that he calls “functional medicine.” He is also Founder and Medical Director of
the UltraWellness Center. He advises Dr. Oz-Oz’s HealthCorps group and he is nominee to President
Obama’s advisory group on prevention, health promotion, and integrative and public health. Welcome, Mark. [applause]>>Mark Hyman, M.D.: Thank you. Thank you. So as I was, I do talk fast so they-they told
me you were smart enough you could handle it so I think it’s, I should be okay. Now as I was getting my talk ready I realized
that Googlers know more about the future of medicine than most doctors do. And they know
that because Google is very much like the future of medicine. In medicine we have a
new model that’s emerging we call P4 Medicine which is personalized, it’s predictive, it’s
preventive, and it’s participatory. In the same way of Google, it’s very personalized.
You-you get to find out exactly what you’re looking for at the moment you’re looking for
it. It’s also predictive ’cause it predicts, what
Google is [inaudbile] exactly what you’re looking for and it allows you to identify
exactly what you wanna find at any moment. And it’s also preventive ’cause it prevents
you from going down all sorts of roads looking for data and information that isn’t relevant
to you. And it’s also participatory ’cause you have
to take action based on what you find and what you do. So Googlers actually have created a system
that models the future of medicine ’cause the future of medicine is going to be personalized.
It’s gonna look at your genetics, at your environment and how those variations affect
your health in this moment. The future of medicine is taking the data
in your story which is called narrativomics this, the data in your narrative, in your
story and making sense out of that and seeing the patterns in that. The future of medicine is about genomics and
all the omics: the proteomics, metabolomics, the phenomics, which is really looking for
the patterns in the data which is exactly what you do here. And it’s also preventive because we’re going
to be able to understand how to best look at a health map on a predictive model by looking
at all the data points in your story and in your file markers, and tracking that forward
to see what your health risks are and how to create a personalized plan to help you
get healthy and stay healthy. And it’s also participatory ’cause it means
you need to be engaged. It’s not just taking a pill that your doctor gives you because
you’re gonna treat some symptom of some disease and not-not to do anything else except pop
that pill. So it’s very participatory and you have to be an engaged user of health care. So this is, so what struck me this morning
at about 6 o’clock in the morning and-and made me realize that the talk today you guys
are gonna get it because it really reflects what you guys already do and already know,
but it-it’s the medicine of the 21st century. And the unfortunate fact is that it takes
about 20 to 50 years before a medical discovery gets implemented in practice. It took 50 years
for the stethoscope to begin to be used. And-and the future of medicine is-is not going
to be creating a hypothesis, as we do now, and then doing a study and collecting data
and analyzing the data. It’s gonna to be looking for patterns in the data that already exists
and the patterns in your story and the patterns in the biomarkers and using the computational
power we have now to create a model of thinking about disease, disease patterns, and connections
and relationships and linkages in ways that we don’t now. Because medicine is completely
is completely solid as I’ll share with you in a minute. Now this is happening all across the world.
You may not have heard of it. You may not be familiar with it in the words that I’m
speaking to you about it, like functional medicine or P4 Medicine, but you’ve heard
about the concept of systems and of a systems biology. And schools like Johns Hopkins have created
an entire new medicine school curriculum to map to this new concept called Genes to Society. And we don’t realize this but medical education
was established in 1910 and the-the model of education we have now is pretty much the
same as it was then. If you wanna know how a doctor practices you
just look at the early graduate of medical school and things are very difficult and slow
to change. So they’re tryin’ to shift that and tryin’
to understand how the environment interacts with our genes in any moment to create our
phenotype. This is really the-the concept of the future
of medicine which is the moment of health that you have now, the person you are right
now, is created by your lifestyle and your environment, toxins and everything in your
environment, washing over your DNA to create the person you are in this moment. And that it’s really a continuum of illness
not simply on or off, you have this disease or you don’t. One day you have, don’t have
diabetes, the next day you don’t. One day you-you’re free of cancer and the next day
you have cancer. That’s not how disease works. It’s a continuum of shift from optimal function
all the way to full blown disease. It’s the medicine of-of why not what. We’re
trained as doctors to say, “What disease do you have? What drug to I give you?” Instead
of, “Why is this happening? Why does this particular person have this particular symptom
at this moment. What are the underlying causes? What are the mechanisms and pathways and connections
that we can use to link together this information to understand what’s really at the root of
disease? And this is happening all over the world.
Over 40 countries have participated in educational programs at the Institute for Functional Medicine.
There’s 31 medical ed-educational institutions that have been involved. There’s over 13 residency
programs that are exploring this. So this is out there. And today I wanna take you through the lens
of the brain and show you how this model applies. And it applies not just to the brain, but
to all chronic diseases; all the things that are our pain points as a nation, as a, as
a world which we’ll share globally. I don’t know if you know this but by 2020 there will
be less than 20 million who will die from infectious disease. But over 50 million will
die from preventable, chronic illnesses, and reversible chronic illnesses like heart disease,
diabetes, and cancer. So it’s not just in America, it’s globally. So how do you power up your brain? It’s important to focus on prevention because
often as I’m gonna show you with this patient it’s difficult and it can be too late if you
wait too long you can end up with re-irreversible problems with your brain. And-and hopefully you haven’t gotten to this
stage yet about where we can do a lot. Now this is a, no joking, this is a big epidemic.
There’s 1.1 billion people in the world who have brains that aren’t working; they have
depression, they have ADD, they have dementia and there’s all sorts of other spectrum of
brain disorders along the continuum of brain dysfunction. And the question is how is your brain working?
I mean it’s probably a good brain to start with or you wouldn’t be here, but is it working
as well as it can and if not, why not? And how can you make your brain work better? Maybe you have mood issues, maybe you have
a little trouble focusing, maybe you have trouble sleeping, maybe you have trouble with
energy, maybe you have trouble with even cognitive focusing and-and memory. Now we have a lot of insults to our brain
and there’s a lot of damage that happens as a result of things that we do. And there’s
a way we can understand how to change that. When our brain aches we don’t really feel
pain, but it shows up as mood problems or focus problems or attention problems, right?
If you’re, if you have a sore throat your throat hurts. If you have a toothache, you’re
tooth hurts, right? But if you’re, if you’re brain hurts what
happens? You have ADD, you have autism, you have depression, you have dementia, you have
cognitive loss. These are things that happens to your brain as your system becomes imbalanced. And so what we’re gonna learn about is how
if you change your body it’ll change your brain. The inputs you put into your system
create the outputs. And if you change the inputs you’ll get different outputs in terms
of cognitive function, mood, attention, memory, behavior, and so forth. So I’m gonna talk to you a little bit today
about a pretty radical idea. But I think you guys are up for it; which is that the way
we think about disease really is passé. In fact and recently at a conference a CEO of
a major drug company said that in the future there’ll be no more drugs for block buster
diseases only drugs for block buster mechanisms. And the reason for that is that diseases don’t
exist. Not really in the way we think they do because just the way the world looks flat
and it’s not and just the way it-it appears that the earth seems to be the center of the
universe, it’s really not. Diseases also appear real but their simply the downstream effects
from upstream mechanisms and causes. So we’re gonna talk about how your brain works
and how we do things that harm it and what we can do to help it and how we can optimize
your brain function, your focus, your mood, and your performance. So the way we do this, and-and I’ve written
about this in the books. Many of you got lucky to sit in a seat with the UltraMind book which
this is what this is and the other ones have the weight book. I don’t know if it’s applicable
to you, but you can swap the books around and this is a personalized prescription for
creating a powerful brain. It’s-it’s not a generic program; it’s something
that can be personalized and-and individualized to match your specific issues. And we’ll talk
about why that’s important. And it’s based on this notion that P4 Medicine, which its
clinical model is functional medicine. Most of what I’m gonna tell you is in the
book. There’s over 400 references in the book; there-there’s really based on seeing thousands
of patients over 15 years using this model. Here’s the practice that I have in Lennox,
Massachusetts which is having an ice storm now so I’m thankful I’m not there. So the basic notion here is that if you change
your body, you’ll change your brain. We all know that the mind influences the body
but we don’t think so much about how the body influences the mind. And someone mentioned
to me earlier that they were having depression and that they were gonna go see a psychiatrist
and they were probably gonna get a drug and said, “Gee if I knew that I could change what
I’m doing to change my mood, I might do that.” So people don’t really make the connection
between what the inputs are and how they feel. We sort of don’t think about it. Somehow we
wait until we get sick to really think about our health, but we don’t notice that all these
subtle problems and symptoms and conditions that we suffer from are really fixable by
addressing the underlying cause. If you guys want a copy of the slides you
can go to drhyman.com/google to-to get a download so you don’t have to write everything down. So this is a pretty shocking idea, but diseases
don’t really matter anymore. As we understand the body as a system our notion of disease
is-is taking flight and it’s, and it’s shifting from understanding disease as a discreet set
of different conditions to understanding the underlying pathways and systems underneath
it. So my hypothesis today is that there really
is no such thing as depression. There’s no such thing as bipolar disorder. There’s no
such thing as ADD or autism or dementia; that these are really systemic illnesses that happen
to affect the brain. And that you have to treat the system in order to fix the problem. So we get stuck in this whole concept of the
name it, blame it, and tame it. We name the disease and then we blame the name for the
problem, and then we try to tame it with a drug. And-and we don’t think in a complex
way in medicine. We get really focused on one disease, one
drug model which is really 19th century diseases. The bacillus that was discovered by Louis
Pasteur and was treated with antibiotic that seemed to work, so we try to apply that to
all the rest of medicine. But that’s actually not how the body works. And-and we really good at labeling things
and naming things. There’s this category of psychiatric diseases called DSM-IV and I was
sitting at dinner with the-the head of the National Institutes for Mental Health in Washington
a few years ago and I said, “Dr. Insel what do you think of this book the DSM-IV which
is the Bible for psychiatrists? He said, “I think it has a 100% accuracy but 0% validity.”
Meaning it’s very good at describing the symptoms people have and putting them into groups according
to their symptoms, but it tells me nothing about the cause for those problems or even
really how to think about them in a way that works. And this is an article from my favorite alternative
medical journal, the Journal of the American Medical Association, which has all sorts of
amazing things that people just don’t pay attention to. And-and they-they-they talk
about dementia in this article and-and our shifts in thinking about it and how when we
study dementia and we look at ginkgo or fish oil or this or that it doesn’t seem to work.
Or we use this drug or that drug. It’s because dementia doesn’t really exist
the way we think it does. It’s simply an end result of a whole series of insults and many
different kinds of insults that can lead to the same common symptoms. So in this article they talk about how that-that
we classify things incorrectly and we’re not very good at talking about the cause. This
is categorical misclassification and etiologic imprecision. Meaning we classify by symptoms
instead of by cause which is really what we’re going to be doing in the future. So let’s just take an example. You go to the
doctor and you feel sad and helpless and hopeless and you’re not interested in life and sex
and food anymore; you can’t sleep well; and you even have thoughts maybe of killing yourself
from time to time. And your doctor goes, “I know what’s wrong with you. You have depression.” But that’s not what’s wrong with you, that’s
just a name of those collection of symptoms. It doesn’t tell you anything about the cause.
It tells you what, it doesn’t tell you why. So for example, someone who comes in with
depression might have many, many causes. You might be, for example, eating gluten and you
might have a genetic susceptibility to create problems from this which creates an autoimmune
disease that attacks your thyroid that causes you to have low thyroid function that can
lead to depression. And the treatment is getting off gluten and treating your thyroid. Or you might be having reflux for years and
taking an acid blocking pill which inhibits B-12 absorption which leads to depression. Or you may live in Seattle or work inside
all the time, although you guys are out playin’ volleyball so maybe you get outside and get
some Vitamin D, but you might have a Vitamin D deficiency and have depression and need
Vitamin D. Or you might be taking antibiotics for acne
or have frequent colds or sinus infections and take antibiotics that destroy your gut
flora. And that changes the microbiome in your gut and changes the regulation of the
immune system in your body that leads to inflammation. And an inflamed brain is also a depressed
blane, brain. Or you might love sushi ’cause I see you had
lunch today and may be full of mercury. And mercury can cause depression. Or you may hate
fish and have Omega-3 fat deficiency because you don’t like fish. And Omega-3 fats are
critical for brain development and mood. Or you might love sugar and eat lots of sugar
and soda which actually leads to something called pre-diabetes or metabolic syndrome
which has been cause of depression. So the treatment and the diagnosis of each
of these things is very different and you have to ask the question why, not what. So in-in medicine we come up with a lot of
solutions and often we find out they may be the wrong thing later on. This is an ad from 50 years ago that more
doctors smoke Camels than any other cigarettes and 113,000 doctors are coast to coast. So
you can substitute more doctors recommend Prozac or Lipitor or any other drug for this
or that and in 50 years how are we gonna be looking at this? In fact think about it, is depression a Prozac
deficiency? Right? Is it, is this a drug deficiency or is it some other imbalance in your system
that’s driving this? Now in the future we’re gonna be shifting
away from just saying, “You have depression. Take this antidepressant,” to “Oh this is
a-a symptom of some other factors. Let’s find out what those factors are. Let’s look at
your whole biology as a system.” This is called systems biology. And redefine disease based
on causes and mechanisms and not on labels. And we’re gonna be shifting from the silos
we have which are all the ologies, the specialties, that we have in medicine and we go to a doctor
for every different part of our body. We take a pill for every ill. We’re gonna shift into thinking more about
complex networks and systems. We’re gonna be moving away from the 12,000 labels of diseases
we have in our code book to an understanding of biology as a, as a network or a system. And it happens at a, at a very fundamental
level. We’re-we’re discovering this in biology that your-your physiology is a web; that it’s
a network and that it happens at a genomic level, at a metabolic level, at a disease
level, and there’s patterns that connects all of these different pathways and things
together and link them together. And there’s also a network at a social level.
In fact if your friends are overweight you’re more likely to be overweight than if your
relatives are overweight, or your mother or father’s overweight. So there’s a huge component of-of-of understanding
the networks and connections between things that are important. So just as, for example, depression can be
caused by many different factors. One causative agent can trigger many different diseases.
For example, gluten can cause depression. It can also lead to autism. It can also cause
rheumatoid arthritis. It can lead to osteoporosis. It can lead to irritable bowel syndrome or
even inflammatory bowel syndrome. Sorry some of you guys are eating lunch. And even heart
attacks, and cancer, and dementia. In a recent study of 30,000 people they found
that people who had low level reactions to gluten, not even a full blown celiac disease,
had between a 35 and 72% increase in their risk of death from heart disease and cancer. So we have to reframe how we’re thinking about
these things. You can go to the doctor and have all these
different conditions, you’re gonna get a certain specific treatment based on suppressing the
symptoms. You’re not gonna get a treatment based on the cause. And so for all these conditions
you might have a result of relieving the symptoms by treating the-the gluten problem. And this is not just applicable to mood issues.
It’s across the whole spectrum of what we call the B-O-I which is the Burden of Illness,
including the big cost drivers and-and-and things that drive suffering and disease like
obesity, heart disease, diabetes, depression, and mood disorders which are rampant; I mean
the second leading category of pharmaceuticals are psychiatric drugs. And then of course these arise in allergies
and asthma and respiratory illnesses, digestive disorders. I was shocked to find that one of the biggest
cost drivers for a major insurer was reflux and heart burn which is a treatable condition
not using PPI’s or acid blocking drugs but-but using the approach that I’m talking about. Cancer, back pain, migraines, and all autoimmune
disease which affects 24 million people collectively like rheumatoid arthritis, lupus, and MS,
and so forth. These are all things that-that have really
very poor treatments in conventional medicine, but in this new model of systems thinking
that we addresses the underlying causes; a very powerful approach. So the question is: do you suffer from brain
damage, and if you do, what can you do about it? Now this is what our brain should like, look
like, and this is what it may look like if you’ve taken too many drugs or maybe drink
too much alcohol or don’t get enough sleep or drink too much sugar or on and on and on. And-and the good news is though, that if you’ve
injured your brain you can repair your brain. This concept of neurogenesis is very critical
in-in the research. And even in people who are dying they’re making new brain cells.
People who have cancer they, they’re-they’re dividing neurons through a special tag, biochemical
tag, and they find that in rapidly dying people there are actually new dividing cells in their
brains. And there’s also the concept of neurotrophic
factors: things that enhance and optimize our brain function. We were talking about
that at lunch. There’s a molecule for example in coffee and-and in actually the coffee bean
and in-in curcumin and in fish oil that actually help regulate pathways that improve your brain
development and improve connections. So you have both new brain cells, which is neurogenesis,
and-and new connections, which is neuroplasticity at any age. And the cause of our problem with brains is-is
really not a chemical imbalance in the way we think it is. There’s not a Prozac deficiency.
But it’s a, it’s a series of insults that happen over time. It’s our nutrient depleted
diet. It’s our toxic environment, heavy metals and pesticides; it’s our unremitting stress.
It’s various triggers that upset our immune system such as allergens or-or infections. And in many of the things we eat: high fructose
corn syrup, sugar, trans fats, food additives, pesticides, hormones, all influence our brain
function. Also things we do everyday affect it: our
sleep cycles, our circadian rhythms, levels of stress, not-not exercising. Exercising
is one of the best things you can do to actually prevent Alzheimer’s. And a brain trauma, I
saw somebody fall off a swing today out there. I was a little worried, but brain trauma is
not good for your brain and I know they’re your most important assets. You wanna be very
careful. And in certain drugs we use: nicotine, caffeine,
alcohol, in some ways are all injuring to the brain. Caffeine has a, is a double edged
sword. It may help regulate certain pathways that control inflammation, but it also may
damage you by decreasing dopamine and that leads to needing more coffee and then having
this sort of crash and burn cycle where you basically get a little boost and then you-you
fatigue and then you need more coffee and it eventually doesn’t work. So you have to
be careful. There’s certain medications that can have
impact: the statins, and acid blockers, and various things. So, also heavy metals and
toxins. So we really have to understand that depression,
ADD, and autism and dementia are not really diseases they’re really just symptoms of some
underlying imbalances. And they can be nutritional imbalances and
this is really the crux of-of the story here. And this is what I-I talk a lot about in-in
my books and which is the foundation of functional medicine is reorganizing biology into a series
of-of nodes within the network of-of our physiology and the webs of our physiology. And these nodes are really the places we wanna
look for problems in nutritional status. We wanna look for problems with B vitamins
and Vitamin D and zinc and magnesium and Omega-3 fats. We wanna look for triggers of inflammation
in the brain like gluten and food sensitivities and infections and toxins and sugar and molds. We wanna look for hormonal imbalances like
thyroid, adrenal, and sex hormones and problems with sugar. Even our gut and I’ll talk some
a little bit about how the gut plays a role in-in our brain. And then of course toxic injury: heavy metals,
pesticides, molds, loss of energy in our cells, very important. And loss of energy in our
cells and our capacity to produce energy creates a decreased brain function and performance
and then any sort of chronic or acute stress. So these are the areas that we pay attention
to and we-we navigate to and filter our information through a new set of lenses. And the problem with medicine is that the
treatments we use don’t match the cause. So if you’re eating gluten and you have depression,
taking Prozac’s not gonna help. Or if you have a folic acid deficiency, for example
you get a 6% benefit from an antidepressant. If you actually correct the folic deficiency
the benefit of the drug goes up 44%. But I say, “Why not just try the folic acid first
or the folate first and then if it doesn’t get better use a medication?” So let me make this a little more granular
for you and show how this works in a particular story of-of a boy who came to me with Attention
Deficit Disorder. This is a rampant problem. There’s 12 million
kids who have problems and this arises in all the whole spectrum of disease like autism
over the last 20 years in extraordinarily high rates. We’ve gone from 1 in 10,000 to
1 in 100 kids who have autism. And the-the-the hypothesis here is that the
cure for brain disorders is really outside the brain. It’s by treating your system and
your body. So we have to ask, “What’s going on? Why are these kids having this problem?” And this is Clayton; this is every kid in
America. He came to me he had 11 diagnoses, he’d seen five specialists, was on eight medications.
He had asthma, allergies, anxiety, ADD, and anal spasms, and that’s just the A’s. Now he had lots of other issues: digestive
problems, and he had anxiety and fearfulness, and he was very disruptive, he had bad handwriting.
And-and these are his list of problems. You can see it’s a very long list and he was a
long, a long list of medications at 12 years old. And nobody asked how is everything connected
in this boy. Nobody wanted to look at how things are out of balance. How is he sort
of off kilter? And-and nobody wanted to understand how we can look at the underlying factors
that are driving his symptoms. So we began to do things that put his system
back together and it required a sort of set of complex changes that-that looked at the
underlying factors. Now we knew he was on antibiotics, he had
frequent infections, he had a horrible diet, he ate junk food, and we knew that-that he’d
seen a bunch of people, but no one asked how is everything connected. So we were asking the wrong questions. Now this is the map I used to help figure
out what was wrong with him. Which is rather than seeing a specific disease and treating
it separately like his ADD and treating that with Ritalin, and his asthma-asthma with a
certain inhaler, and his allergies with an antihistamine, and so on. I said let’s take
a map and look at how all these things are connected. So it just looks like probably one of your
white boards as you’re doing your-your-your programming, but this is a model of-of this
little boy, Clayton, who had some predisposing factors of poor diet which led to, and antibiotics
for lots of infections when he was younger, which led to disruptive, disruption in his
digestive system. And that led to various disruptions in his
immune system. And that led to also to antibody development related to foods and also gluten. So that disrupted his whole system and that
affected his-his brain. He also had lead in his system and he had also nutritional deficiencies. And this was obvious just from talking to
him ’cause he had, for example, muscle cramps and anxiety and insomnia and-and-and headaches
which were all signs of magnesium deficiency. He never ate fish so I knew he had Omega-3
fat deficiency. He was always inside playing video games so I knew he had Vitamin D deficiency.
He also had very poor diet, he didn’t eat vegetables, so I’m assuming he had low levels
of antioxidants like beta carotene. And he had a high processed diet and it was high
in sugar. So these were all clues to me and patterns
that I see and I-I see this disruption in his basic physiology and I wasn’t sort of
treating each disease separately I was saying, “How do we create balance back in his physiology?” “I’m afraid that your irritable bowel syndrome
has progressed. Your now have furious and vindictive bowel syndrome.” [laughs] And I think what people don’t realize is that
an irritable bowel often causes an irritable brain; that the disturbances in the gut flora,
in the levels of inflammation in the gut trigger inflammation in the brain. And that leads
to mood and cognitive disorders. So we really spent our time looking at all
these nodes and this network and this system that are all dynamically interactive. These
really aren’t separate things; they’re really just, we’re just using this as a model for
thinking about disease, but it’s-it’s a model that-that can explain most chronic illness. So instead of thinking about diseases, I think,
“Well what’s goin’ on with his immune system? How’s his digestion? What is his nutritional
status? How-how’s he detoxifying? What’s going on with his-his gut?” So these are the things that I really look
at. And we found when we looked under the hood, and people say that modern medicine
is like trying to figure out what’s wrong with your car while listening to the noises
it makes, right? We need to look under the hood a little bit. So not everybody needs all these tests and
I just use this for you as an illustration, but I-I’ve been able to actually predict what
most of these-these results would be just by talking to him; just by his narrativomics,
by his story. So we found out he had low levels of certain
amino acids and low levels of fish oil, low levels of minerals like zinc and magnesium
which we predicted; low levels of Vitamin D and E ’cause he didn’t like grains and he
had B12 and B6 deficiencies which affect mood. He also had immune disturbance with allergies
as we talked about and elevated antibodies to gluten. And he also developed yeast problems
in his gut because had lots of antibiotics. And when we checked for mercury and lead we
found he had a high level of lead which can really disturb his-his system. Now this might look like one of your white
boards too and, or computer program, but essentially this the-the sort of dynamic interactions
that happen at a molecular level that drive downstream symptoms. So let me just sort of walk you through this. This is an enzyme and enzymes are simply catalysts
or helpers in biochemical reaction; they turn one molecule into another. If there are things that stop this enzyme
from functioning like heavy metals, mercury, lead, it jams that biology and that creates
a whole series of things so this wheel can’t turn and you end up, for example, not being
able to methylate or turn on dopamine receptors. So you can’t focus or pay attention or concentrate.
It prevents the energy production to preventing adenosine which needs to be methylated and
so you lose energy in your body in your cells. It prevents methylation of neurotransmitters
so you can’t produce serotonin and-and-and epinephrine and adrenalin which help you focus. And you also can’t produce antioxidants like
glutathione which protect you against inflammation and help you detoxify from heavy metal; so
this will all jam if something is-is-is poisoning this enzyme. The good news is there are ways to help this.
For example, you can unblock it using methylcobalamin which is a special form of B12 that actually
can open up the system. And I’ve seen kids for example with attention
deficit or autism or behavior issues, you give them the right form in the right way
of this methylcobalamin and they literally focus and pay attention. You know these kids
don’t look at you, they don’t look at you in the eye, they don’t pay attention; they’ll
literally wake up and they’ll focus and they’ll pay attention, be alert. Very interesting to see how you can play with
this web of physiology by dealing with the root issue as opposed to dealing with the
downstream symptoms. And here are just some of the tests we did:
looking at his food sensitivities, genetic predispositions, looking at heavy metal levels,
looking at his gut function, looking at his-his levels of-of mitochondrial function, and all
sorts of things that are novel biomarkers that don’t specifically look for a disease
but look for patterns in the data; look for associations and connections and linkages
to help us understand what the drivers are of disease. And actually we can work and play in this,
in this data field and change the outcomes by simply taking out the bad stuff and putting
in the good stuff. And it helps create balance in the body. So how did I treat him? I gave him a healthier
diet, I took away the junk food, I took away the things that his body is reacting to in
his immune system, I cleaned up his gut with some drugs that clear out the bad bugs like
antifungals, I got rid of his heavy metals, and then I-I gave him a real food diet and
some nutrients that were based on his story and some of the testing that helped to regulate
his biochemistry and change his gene expression and changed how he was actually functioning. And I gave him things to help his gut and
the bacteria and normalize his gut function. And you know what was striking to me was no
not that his symptoms got better and his stomach aches and headaches and his allergies and
his asthma and his ADD went away and that he had good school performance and he was
doing better in every way, but what struck me was what happened to his handwriting. This was his handwriting before he came to
see me and I was downstairs taking a tour and I saw some white boards that sort of looked
like this actually. [laughter] And maybe [laughs] some of you have some of
these issues, I don’t know but. The-the result of two months later looking
at his handwriting was this. So I had to ask myself when I saw this what
was going on? How did his brain go from dysfunctional to functional; from incoherent to coherent?
How did the asynchrony and coherence happen in his system? I didn’t treat his brain, I treated his body.
I treated all the imbalances that I found. And-and really as we think about this were
looking at these sort of biological origins of-of dysfunction, this complexity science
and how genes interact with our, with our environment and our diet and out food and
how various insults like toxins or nutritional deficiencies or immunological factors, stress
all play a role and change the brain conditions or the conditions in any area of our body,
right? And they, and that leads to abnormal cell
function and cell structure and organization or chemistry and that leads to altered processing
and signaling and gene transcription and the whole proteomics, metabolomics phenomics which
is the end result of phenome is the expression of your genes at any moment. And-and that’s when we see the downstream
observable symptoms which we call ADD or depression or dementia. But those become less relevant
as we understand the underlying causes in disease. Now this was me 15 years ago and as you see
this is me today. And I-I began by, this journey by being sick myself and understanding this-this
problem in a way that forced me to look at things differently. In-in medical school I didn’t learn what I
needed to know to solve my own problem. So I had to go and begin to look at the data
and look at the research and see what was going on out there in medicine to find out
how things really work. How does the body work? What are the, what are the basic organizational
principles that on which our biology is founded? How, it’s really very sort of existential
question and it’s a paradigm shift so profound it’s as great as when Columbus said, “The
earth is not flat,” or Galileo said, “The earth is not the center of the universe,”
or when Darwin said, “Species don’t just arise fixed in their current form but they evolve.” In the same way diseases don’t just show up
fixed in one moment to the next, they evolve in a continuum. And this is a really new-new
radical idea in medicine that has not been adopted yet. But at the Institute for Functional Medicine
we have a textbook if any of you are really interested in this you can learn more about
it. And it’s really based on this-this notion of dealing with the roots of the problem.
Most of the ologies are out here in the branches and the leaves of the tree and we focus on
this-this diagnosis by organ, right? And then we-we don’t really look down here
at what are the underlying drivers of disease and what are genetic predispositions in our
thoughts and our feelings and how those affect us. We-we know that our thoughts and our feelings
actually talk to our DNA; that our food talks to our DNA and changes its expression moment
to moment. And that leads to physiologic changes that lead to imbalances as in these sys, in
these systems that I mentioned. So these are the systems that we looked at
with this little boy and that’s what really I focused on in practice and that’s what we
teach at the Institute for Functional Medicine. Now many of you think you sort of got genetics
from your family. I had lunch with somebody today who said they have a family history
of diabetes and heart disease and dementia and Parkinson’s and these are things which
we sort of somehow believe we’re destined to experience because they are in our genetics. But DNA is not your destiny. In fact, your
genes are fixed but the expression of those genes is not fixed. And let me show you some pretty radical information. This is talking about, for example, Parkinson’s
where we know that-that there be certain pre-predispositions to Parkinson’s and there’s, but there’s a
dynamic interaction between the genes and the environment to-to lead to certain problems
in our biology like inflammation and free radicals and energy production which then
leads to cell death. And we know, for example, I was talking about
earlier the NR2 pathway which works in modulating this-this expression of your genes and regulates
things like inflammation. This is a really profound study looking at
the Agouti mouse which looked at these predisposed mice who were predisposed to diabetes, heart
disease, obesity, and cancer; sounds like most of us; and had a lower life span. And what they did was they took pregnant rats
and they gave them certain supplements that were methylating supplements that are-are
nutritional supplements that regulate gene expression. But these are nutrients that our bodies have
used since we’ve evolved and are used across all life species to actually regulate turning
on and off of genes. It’s called methylation. So things like B12 and folate, zinc, and so
forth, B6, they regulate this-this-this modulation of your genes. So they found that without actually evolving
you can create what we call epigenetic changes that tag genes and turn on and off genes and
regulate genes to create a different outcome. And the outcome in this little mouse was a
brown mouse instead of a white mouse; a thin mouse instead of a fat mouse; a mouse that
doesn’t have diabetes or cancer or heart disease and lives a long time. And the only thing that changed was they changed
the inputs in terms of the nutrients that regulate gene expression. Same genes, no different
in genes; change in expression. So this is the kind of impact we can have
and it’s enormously important we’ve seen this go in reverse. This is the Pima Indians who a hundred years
ago were thin and fit and had no diabetes, obesity, or heart disease. And now 80% have
diabetes and their life expectancy is 46. And in one generation they went from being
really relatively thin to being enormously obese and now they’re the second most obese
population in the world. Their genes didn’t change, but the environment
changed and the expression of those genes changed. So what we have to realize is that food isn’t
just calories. It’s actually information; it talks to our DNA. It talked to our epigenome
and it transforms our biology in a moment to moment way. So the most powerful decision you have every
day is what you put on your fork or what you put in your mouth. Literally with every bite
are talking to your genes. And it’s-it’s as well worked out scientifically it’s not just
a theory. We understand how this works. And we see changes in our phenome that leads to
for example increases in obesity. Now we’ve seen obesity rates triple, double
triple, quadruple across the world in a very short time. We’ve seen China; 30 years ago I was in China
and I never saw an overweight person. Now there’s-there’s tremendous amounts of obesity
and they went from having no-no diabetes to having 93 million diabetics in-in less than
a generation in China. And the reason is that they’re eating different
food and it’s quickly changing their biology. The bad news is is that as your belly size
goes up your brain size goes down. So if you have a fat stomach you have small brain. You
shrink the hippocampus which is the memory center in your brain. So this correlation is not just there for
cognitive function and memory, it’s also there for depression. More likely you are to be
depressed if you have metabolic syndrome. The more likely you are to get cancer and
heart disease and all these factors that have impact on your brain. And-and we’re-we’re sort of inundated with-with
sugar. We went from less than 10 pounds per year per person a hundred years ago to 185
pounds per person per year now. And I know I don’t have that much so that means some
of you are having a lot more; that’s average. So we have a tremendous problem and-and we-we
drink a lot of our calories. So if-if you look at the caloric intake. For example, if
you just drink one soda or drink a day and that has about 225 calories that’s about 90,000
calories a year, that’s about in terms of 3500 calories per pound, that’s about 20,
25 pounds of weight gain a year just from one drink a day if you don’t equalize your
calories. And the thing about liquid calories is that
you don’t compensate by decreasing your solid food intake. So you actually will-will gain
weight. If-if you have one way to lose weight and gain health in this, in this country that’s
easy to do it’s don’t drink your calories. Now you might think, that this was in the
New England Journal of Medicine that you can, you can just do things like liposuction and
get rid of all this fat and-and have some benefit. And in fact they found there was really no
benefit by removing all this outer fat because the inner fat wasn’t removed by the liposuction.
So all their metabolic parameters: their blood pressure, their blood sugar, their cholesterol,
their inflammation levels, were not changed at all; and so there was no impact and then
we see the opposite happen. If you take someone who does a gastric bypass
they can’t eat. All their metabolic markers change even though they don’t lose weight
that much because their inputs are different and it happens very quickly. Now there may have been some psychological
benefits in this patient that was reported in New England Journal because before liposuction
she was wearing a panty and after she was wearing a thong — [laughter] so there may be some benefits, I don’t know. [laughter] Now how do you fix your brain? I’m gonna give
you some take homes and then were gonna open it up for question and answer. The-the concept here is that if you heal your
body you can power up your brain. And that you can customize the prescriptions for powering
up your brain other than just a generalized lifestyle program. So this is a sort of a generalized wellness
program or what I call Lifestyle 1.0. This is Lifestyle 2.0. This is personalized wellness
lifestyle recommendations that-that are based on this model of systems biology or P4 medicine. So there’s some basic concepts that work for
everybody, right? Which is eat right for your brain. Tune up your brain chemistry with supplements
and I’ll talk to you about those in a minute. The UltraMind Lifestyle which is essentially
common sense: exercise which increases what we call B-D-N-F or miracle grow for your brain;
fertilizes the increases in connections and neuroplasticity. Sleeping is critical; if you used to sleep
seven, nine hours a night a hundred years ago now we sleep seven hours and that two
hour decrease not only affects our cognitive function in focus and depression, it causes
depression, but also causes obesity ’cause it drives appetite. I know when I worked in the ER I used to be
hungrier because I wouldn’t sleep so I would crave more sugar. So we found that if you
reduce sleep by a couple hours a night in young healthy men they’ll increase their levels
of ghrelin which is the hunger hormone and decrease the hormone called PYY which leads
to increases in sugar cravings. So it’s a big problem. Learning how to find the pause button is ke-key.
We all know how to work hard and we all know how to produce, but most of us don’t know
where our pause button is. We don’t know where the off switch is. Very poor at, you have
massage here which is fantastic, you have fitness and play, so I think you have tools
here at your, at your service to do something that can help you switch on the pause button.
And it’s critical because you have to have active relaxation. You can’t just do nothing
and expect your body to relax. And we were talking at lunch about this concept
of heart rate variability which is a big predictor of health. And that’s really how complex your
heart rate is. So the-the least complex heart rate is a flat line; you don’t want that,
right? [laughter] More complex, the healthier you are. So marathon
runners and people who are very fit have very complex heart rates, beat to beat. It’s not
72 every minute, it’s 72, it’s 71, it’s 69 1/2, it’s 73 1/4, and it just varies from
beat to beat. That indicates health and that’s something you can measure; you could even
measure it on a device like an Android and just have your-your-your pulse taken and it
measures the complexity of your heart rate. And that’s an incredible predictor of health
and of-of disease and mood and cognitive function. And it’s something that is directly related
to your ability to reduce stress and to modulate the stress response in your body. And of course there’s things that you do everyday
thought lifting, you don’t have to worry about that that’s using your brain; you do that
and you’re good at it. And also living clean and green which is removing
insults from your brain. So and I’m, I was really pleased to talk to Olivia here who
told me that they-they don’t serve foods that are on the dirty dozen list in terms of pesticides,
for example. They have water filters which is great. So how do you eat right for your brain? What
do you do? And-and these are really common sense things,
but one of the things that I think has-has been overlooked in a lot of care is that there
is certain foods in our diet for various reasons that have to do with hybridization, have to
do with genetic changes in the foods, have to do with changes in our gut flora, that
drive inflammation in our body. And a lot of people have brain allergies and
brain fog and brain dysfunction and they don’t know it until they stop eating these certain
foods. And the two biggest triggers are gluten and
diary which is the wheat, barley, rye, oats, spelt, kamut, these grains that-that you should
be alright to eat but actually drive inflammation in a lot of people. Getting rid of the toxins, the food additives.
I mean I don’t know how many people have Diet Coke but aspartame is-is a neurotoxin. It
actually increases what we call excitotoxicity that increases something called glutamate
which overexcites your brain cells and causes cell death. And it, and a lot of people have extraordinary
symptoms and that we know are connected to what they’re drinking and they may have headaches
or migraines or other things. Eating real food. You’ve heard Michael Pollan
speak. He talks about eat real food; not too much, mostly plants, that’s a good thing.
And-and I think that’s really sort of common sense eating lots of fruits and vegetables. I mean I think less than 5% of Americans or
3% get their recommended five a day fruits and vegetables. Lots of fiber; good quality
protein; and Omega-3 fats which are incredibly important for your brain; a multi-vitamin
is also very important and-and this is a whole concept that I think hasn’t really been talked
about enough in relationship to the brain, but your brain runs on nutrients. What do nutrients do? They-they actually are
the helpers or the co-factors for all the chemicals and reactions in your brain. And if you don’t have adequate levels of nutrients
you can’t actually regulate your brain function properly. So having adequate levels of nutrients
particularly the methylating nutrients: B6, folate, B12, Vitamin D, Omega-3 fats, these
are critical for brain function. And then we personalize the care based on
optimizing your nutrition, balancing your hormones, cooling off inflammations, fixing
your gut, all these nodes in the network. We help to tune them up. It’s like a metabolic
tune up. We help you detoxify and boost energy in yourself and we help you learn how to calm
your mind. And-and-and what I do is I have a bunch of
stories here and cases that teach you how to treat the fire and not the smoke that-that
sort of go through this a little bit. And I-I thought maybe I would just stop here
rather than go through all these stories ’cause I’ve given you the broad view and-and invite
you to ask questions and to explore and to sort of think with me about how you can power
up your brain a little better. So thank you and I look forward to some questions. [applause]>>Liv Wu: Are there any questions? [pause]>>male in audience #1: I was wondering what
your thoughts are on how if all of this, if your program is very personalized how does
that stack up in a world where all of our results are judged by clinical trials and
everything that can’t be personalized? You know you look at a single drug and they
say, “Well in a population, here’s the results.” Your technique doesn’t work with that.>>Mark Hyman, M.D.: Yeah. Well you’re-you’re exactly right. And I was
at a NIH think tank recently on complexity in-in-in systems research. It’s not something,
and I have funds and research is driven by drug development which is a single drug for
a single disease looking at a single end point. But we don’t live like that. That’s not human
beings. In fact if you look at clinical trials they don’t really reflect real people in the
real world. And-and they’re helpful in certain ways to identify the benefits of certain treatments.
And-and-and you have to look at the collective data not this-this sort of evidence based
they call it the randomized clinical trial or control trial. These-these actually distort the-the larger
body of research which is that the basic science, the-the epidemiologic research, the observational
research, and the whole body of-of data points together. And-and if you look at actually the practice
of medicine today very little of it is actually evidence based. Probably 70% of it doesn’t
have clinical trials to support it. And-and this model has to be looked at differently.
I-I think that the instructive kind of work that Sergey’s doing looking at-at patterns
in the data and collecting large amounts of data and then looking at-at-at results based
on that as opposed to the-the sort of traditional way we do science which is at a glacial pace,
is really the future of health care. And-and this model lends itself perfectly to that. Yeah.>>male in audience #2: I’ve got two questions
so I’ll take turns with another person. So consumers are confused, right? Like what’s
the common thread running through all this? They’ve got [inaudible], [inaudible], about
reversing heart disease [inaudible] reversing diabetes, and then your supplements [inaudible]. So keeping things simple what’s common thread
that’s running through all these different speakers and experts that we should do? Like
something actionable that we should do?>>Mark Hyman, M.D.: Right, well I think the
common thread, some of the simple things are-are really important and I sort of talked about
just-just briefly which is realizing that food is information and that the quality of
the food and the type of food you put in your body changes your gene expression. So you have to have a healthy respect for
that and-and also-also understand that a lot of the symptoms that you have currently are
the, are the result of some input that’s going in and you can change that input and have
a different outcome in terms of how you feel. ‘Cause most people don’t connect how they
feel to what they’re eating or doing. So simple things like changing your diet,
getting enough sleep, exercising, taking a few nutrients are simple things that you can
easily implement. And in fact the food service here’s so fabulous at Google it’s not even
that hard, and see the outcomes. And I’ve talked to a number of people in the
audience today who actually came to me and said, “Well we tried this, we did this, and
we saw these changes. And we can do this ourselves.” So there-there-there’s some very simple common
sense threads that run through all of it and I think if you listen to all the speakers
that have come and all that are gonna come, we’re all saying similar things. The unique thing that I’m really saying here
is that, is that this is really not just about general wellness program this is about beginning
to understand the roots of illness and-and creating a model that’s based on this-this
concept of P4 Medicine or personalization. And that-that-that actually requires some
algorithms to help you figure it out. And I-I think that’s what’s so exciting for
me to be here at Google is ’cause you guys understand how to turn words into math. And
you-you can take the words in a person’s story and you can take the biomarkers and data points
and we begin to create algorithms that help to customize and personalize care and treatment. And using feedback mechanisms through various
tools that we can develop that-that help us create the quantified self in a sense and-and
get that immediate feedback. So we can customize and personalize it. So while there is some general concepts that
are common to everybody it is also important to realize that not one size fits all. Yeah.>>male in audience #3: You mentioned some
of the tools we have here at Google to manage stress. Can you quickly walk –>>Mark Hyman, M.D.: [laughs]>>male in audience: us through.>>Mark Hyman, M.D.: Well you’re an expert
in that. He’s head of, well what’s the department? Massage services? [laughs] So I-I think the things that-that you have
that I, that I’ve just noticed is you have outside. So there’s lot of play out there.
There was all kinds of devices and courts and sand and volleyball and all sorts of things
to-to play and have fun. And that’s a way to reduce stress.>>male in audience: Right. Can you walk us
through what happens in the body if we do or don’t manage stress well?>>Mark Hyman, M.D.: Absolutely. So in terms of stress one thing we talked
about is heart rate variability. Stress leads to increased weight gain around
the middle. It leads to high cholesterol. It leads to high sugar. It leads to inflammation
in the body. It shrinks your brain in the hippocampus. It causes depression, it causes
cancer, it can cause heart disease. I mean these are well described phenomena that happen
and also can make you feel badly and disrupt your-your normal cognitive functioning. So-so looking at stress and its impact on
biology is-is-s very [inaudible]. I talk a lot about it in my book. But in terms utilizing
tools there’s a lot of stuff you have here: the massage, you have exercise, even food.
You can stress your body by eating the wrong foods. Having too much caffeine, too much
sugar, these actually raise epinephrine, adrenalin, cortisol, all of which damage your-your biology
and your brain. Hi.>>male in audience #4: Hi. Dr. a bit of a
plug for you for about a year and a half ago I read your book and followed the UltraMetabolism
Diet and literally within a week or two sleep, stress level, certainly skin rashes, stomach
problems all of that just kind of went away and-and continued to kind of stay away as
I, as I, as I continued to stay on the eating the-the right foods. I’m-I’m so fascinated by the gluten thing.
There is something, so I try to get rid of it completely from my diet, but is there something
good about it? You-you-you see a–>>Liz Wu: It tastes good.>>Male in audience: and start hearing a lot
more about it, but you can eat gluten free foods that are just, almost just as good
–>>Mark Hyman, M.D.: Yeah.>>male in audience: and are getting better.
What-what is it about the food that it-it is good or why do we keep using –>>Mark Hyman, M.D.: Why is gluten here and
to it’s –>>male in audience: Yeah.>>Mark Hyman, M.D.: Well we choose grains
when we start agriculture and gluten was one of the grains that was in wheat that we ate
a lot of and it became part of our diet as we became an agricultural society. But our genes change .2% every 20,000 years
and we only became agricultural about 10,000 years ago. So from an evolutionary point of
view we’re not in complete harmony with eating a lot of grains. Wheat is a particular unique grain in that
it has a very unique protein called gliadin and this-this plus other findings that we’re
seeing now, for example, like wheat germ agglutinin and-and gliadin affect our-our gut function
and change our immune system and lead to things like rashes. Like you said you had rashes all over your
body that can be from inflammation that’s triggered from gut. And when you stop eating
it the rashes went away. And you had side effects like your-your brain woke up, you
had more energy, you could focus, and you lost weight as a side affect ’cause if you’re
inflamed you actually gain weight. So they may cause inflammation like we will gain weight. So I mean I like bread like the next person
and like-like flour and it’s just sort of delicious products, but the reality is that
about 30% of us have a problem with it. And as I was talking at lunch we-we know that-that
increasing portions of our population are sensitive. They had 10,000 pooled samples of blood from
50 years ago and they compared it with 10,000 pool samples today, and they found that there
was a real increase of 400% in celiac disease. And that’s not even latent celiac or latent
gluten problems which probably affect many more. And we know that if you have latent celiac
you can increase your risk death from heart disease and cancer by 35 to 75%, and that
99% of people who have this problem are not diagnosed. At-at Cigna they did a study there 11 mil
–>>voice in audience: [inaudible] [pause]>>Mark Hyman, M.D.: At-at Cigna they did a
study there of 11,000 subscribers and they found that there was a 30% reduction in cost
in those people who actually identified gluten sensitivity and eliminated the gluten. So not only will it make people feel better,
but it-it had a direct impact on health care costs. And 99% of the people who have this
problem don’t know it. [pause]>>male in audience: So I was –>>Mark Hyman, M.D.: I want to say one other
thing about that. People say, “Why all of a sudden do we see
this increase in gluten sensitivity?” There’s a couple of reasons. One is that I
think we’ve changed the-the actual protein structure of the gliadin in the wheat and
that we know that as a fact and-and that may have different immunological affect on the
body. But also we’ve changed our digestive system
and our, what we’ll call our microbiomes. I don’t know if you know this but there’s
more foreign DNA in your body than your native DNA from the microbes that live within you
and on you. That there’s more foreign cells in your body
than your own cells from all the microbiome. And they have enormous impact on our health
and our immune system. For example, in Africa they did a study recently
of hunter-gatherers they found that they had a whole different profile looking at DNA analysis
of the bugs in their gut than we do today. And that are in the comparable group of-of
people from Europe. And those-those changes have led to more allergies,
more asthma, more autoimmunity, and-and I believe also more heart disease, and many
other things we see in obesity. So I-I think this is, this is just the tip
of the iceberg that we’re seeing here. Yeah.>>male in audience #5: So I’m interested in
helping people like you make a long and lasting impact. So my question is –>>Mark Hyman, M.D.: That’s good news. [laughs]>>male in audience: Who will continue your
work after you? How do you spread what you’re doing, how do you spread behavioral change
in the consumer world like wildfire?>>Mark Hyman, M.D.: That’s a great question
and I’ve spent a lot of time thinking about that. And I don’t have a ton of time to answer
it, but I’ll give you the short answer which is I believe we need to create a disruptive
model for health and-and to-to create what-what a friend of mine recently called a “disintermediate
strategy.” Where we empower people to gather their own
data about themselves, both through questionnaires and through bio-biochemical and various blood
specimens and body fluid data; to input it into a computational model that recognizes
patterns that is predictive of what the imbalances are in their systems; that then can be prescriptive
for what to do in a personalized way to identify the problem. So, for example, you [inaudible] could have
put in that you had rashes and that you’re tired and you’re a bit of gaining weight and
you have x, y, and z symptoms. Then you might have been suggested to maybe do certain types
of tests and ask your doctor, or you might be able to actually do home testing to actually
look at some of these things. And then there may be other devices you can
look at to measure it through very sort of quantified self techniques that we’re learning
about. What-what’s going on the other biometrics. And then you put all that into the system
and then it gives you certain outputs that tell you what the likely probability is that
you have gluten sensitivity or that you have magnesium deficiency or that you have trouble
with your gut flora ’cause you’ve taken years of antibiotics for acne or all sorts of patterns
and correlations and relationships that we know exist that are out there in the data. And this is what was so extraordinary to me
is that the scientific data has not been looked at as a collective whole. It’s like, it’s
like we have the answers already. It’s like Dorothy and her-her ruby red slippers we-we,
she can go away any time she wants. We have all the data points we need in the
current scientific research that are laid out like puzzle pieces strewn across the floor
and nobody’s put the puzzle pieces together. And I-I think in terms of what-what you guys
do here at Google that’s-that’s so extraordinary for me to think about is how do you take that
computational understanding and that ability to-to sort of use math to solve problems and
apply that to biomedicine and systems biology. That’s what’s exciting. I-I know you guys actually have the answer
to the world’s health problems right here.>>Liz Wu: Thank you –>>Mark Hyman, M.D.: You don’t need me.>>Liz Wu: very much. Thank you. It’s two o’clock. Mark will be over here signing
books.>>Mark Hyman, M.D.: I’ll answer more questions
as I’m signing books, too.>>Liz Wu: Yeah.>>Mark Hyman, M.D.: Thank you so much for
the time. I really appreciate it. [applause]

54 thoughts on “Dr. Mark Hyman | Talks at Google

  1. I loved this. I was riveted. Thank you, Dr. Hyman, for an insightful and enthusiastic presentation. I know there was a lot of information given very quickly, but for someone like me who is already familiar with health-related issues and nutrition, it was done at the perfect pace. By presenting at Google, I think you just did a lot for the advancement of Functional Medicine.

  2. @RhunDraco I left that comment a while ago and I don't even remember why I said that. I guess I'll have to watch this and be frustrated all over again.

  3. @RhunDraco I'm actually tempted to just send you a personal message outlining in detail every stupid thing that was said in this presentation, but you seemed to be speaking for everyone else reading these comments, and I'll keep it here for now.

    What he says about depression and treating the symptoms and not the cause is fine if you want to have philosophical discussions, but practically, thats an empty statement. If I have depression, and take an anti-depressant and my symptoms go away…

  4. @RhunDraco …then who cares about gluten? The whole point of antidepressants is to reduce/prevent the symptoms of depression. The symptoms ARE depression.

  5. Can addressing our diet (including food sensitivities and allergies), sleep patterns, exercise habits, and the level of toxins in our body radically transform our brain function and deeply influence mood, memory, and attention? The answer is yes!

  6. @InnerSmile72 As someone who's had conventional medicine fail him I find myself understanding functional medicine more and more. An attempt to follow a healthier lifestyle has helped me more then any advice I'd gotten from a conventional doctor and I have to thank this doctor for his help. I'm not saying its the fix of all health problems, but to completely dismiss what he is trying to say is as arrogant as completely embarrassing it. Some people may find this helpful and its up to them to try.

  7. The ignorant posters are actually funny! If you dismiss what Mark Hyman has to say then you are clearly not understanding what he is saying.

    Be comfortable in your ignorance and keep your hateful comments to yourself.

  8. @MrXSpeaks He's already done it to a lot of people. Go check out his YouTube channel to see cases of people he's helped. And his claim that we manufacture illness is based on the standard American diet which has .been COUNTLESSLY documented to contribute to a host of health problems from diabetes do dementia. That is what it is based on.

  9. I like most of his stuff, I have his books, the problem is he says dairy is bad for you. here is the thing I did some research on how whole fat dairy has been shown to help people lose more weight with same caloires then without. these stuides I googled obesity and calcium and obesity and vita d.

    even dr mercola talks about importance of vita d but I cant see how anyone could produce enough without eating enough sat fat and cholesterol from which vita d and calcium rely.

  10. The only thing that fascinates me more than the fact that he's wrong in so many ways, is that he's even allowed to be talking at AtGoogleTalks. Interesting concepts, yes, but scientifically rubbish. A far more interesting subject is epigenetics, in some ways it's kind of similar to this, only it's more science.

    One (or a small minority) person responded to this kind of treatment! It's science! – WRONG

    A lot (vast majority) of people responded to this kind of treatment! It's science! – CORRECT

  11. I can't believe Google endorses a quack like this, functional medicine? More like a bunch of bs treatments with no efficacy and no basis in science

  12. @bengalslash
    Dr Mark Hyman is very educated physician. He was a school teacher, later became a nutritionist, then became a doctor/MD, spent time in China and studied Holistic/Naturapathic Medicine. There is a lot of science in his educational background.

  13. @talusan909 holistic/naturapathic medicine, which most of which has no basis in science. Anyone who willingly studies that woo has already had the blinds pulled over their eyes. Ultra wellness? What a quack work for give me your money.

  14. @capricious71 if science hasn't yet supported what he thinks, then what evidence does he base his claims on?

  15. It's amazing that I found this video after some of the things I've learned about my own health over the last few months, many of which Dr Hyman addressed in his talk. The huge problem with "modern" medicine is that it's solely concerned with treating the symptoms and not the underlying cause of the symptoms. I'll be buying his book and recommending it to friends and family. I have been seriously ill and am now using some of the methylated vitamins he mentions and it's transformed my health.

  16. @bengalslash Do you really think Google would invite a quack to give a talk to their employees? I think his approach is spot on and you'd do well to look into it.

  17. @jaherd Google is a search engine company. they're not the National Institutes of Health. First off you're arguing since Google is an authority in search engines, they couldn't possibly be wrong when it comes to medicine? How stupid could you be? Hyman is a quack

  18. @bengalslash I have the advantage of having understood what Dr Hyman was talking about as, I'm sure, did those who invited him to speak at Google. If that makes me stupid in your eyes then I'm deliriously happy to be so.

  19. @bengalslash I would say that there are a lot of variables in the factor. It takes quite a while for science to except ideas in certain cases. There is the factor of corporate interests such as profits especially from the Pharmaceutics industry , I know this is a popular talking point, but it is as I see it an obvious truth.

  20. @bengalslash Certain supplements have really helped me turn around my life , this is of course anecdotal. It is a truth that we need many nutrients to fuel our bodies, we are complex biological machines. Isn't it obvious in itself that this is a proper way to maintain health? Of course there are many quacks and Charlatans, Of course there are gimmicks, placebos, memes of pseudo-medical ideas, and down right bullshit, but this isn't putting a triangle on your head and dancing in a toga.

  21. @symbian7 science accepts new ideas after extensive testing to be able to know with certainty that the effect on something is due to what they think it is. Hyman has a lot of things wrong, and he's deep in his woo, and I'm confused as to why Google allowed him to talk, but then again, they're not doctors, they're a search engine company, so.

  22. @jaherd concerned with treating symptoms? Like what? In most cases that's all you can do. Unless you have the power to successfully carry out gene therapy? Do you?

  23. @bengalslash did you watch the video? it's pretty simple: many, many people are ill because of poor nutrition. indeed, i have been extremely ill because of a vitamin deficiency. many illnesses i thought i had were actually symptoms of the vitamin deficiency. once the vitamin deficiency was treated, the symptoms went away. in other words, doctors were treating my symptoms without even attempting to discover the underlying cause. This is the problem Dr Hyman is talking about.

  24. @bengalslash perhaps the problem is that you don't understand what he's talking about? otherwise you would realise that everything he said in the video was true and based on basic physiology. there's nothing controversial at all in ensuring that your nutritional status is as optimal as possible. fewer people would be ill if doctors bothered with such basic checks. are you done now?

  25. @jaherd hardly, quacks that push "alternative" and detest the "western" medicine love to say that modern physicians leave out that you should EAT WELL, when they do not. But quacks like hyman make it seem like this is some secret. Don't put shit in your body, and you'll feel better.

  26. @bengalslash seems to me you're the one doing all the detesting. by "shit" do you mean vitamins? are you aware that some people suffer from malabsorption of vitamins for numerous reasons and so it wouldn't matter how well they ate they wouldn't get enough vitamins and end up ill? you seem to be catastrophically badly informed and out of your depth i'm afraid.

  27. I strongly suggest for people to search for the research of Dr. LIDY PELSSER who heads the ADHD Research Centre in the Netherlands. She had proven that 64% of kids who were diagnosed with ADHD simply had food allergies, and that eliminating it took the ADHD away. It was published in Lancet – "Effects of a restricted elimination diet on the behaviour of children with attention-deficit hyperactivity disorder (INCA study) a randomised controlled trial" + "Diet May Help ADHD Kids More Than Drugs"

  28. I have a serious problem. Over the past 6 months I have rid my diet of all chemical additives. Then I started to shake as if I was coming off a narcotic. I thought it was due to low blood sugar levels but during one bad attack my brother checked my blood level and it was 119. Then I noticed when my neighbor gave me a junk snack I improved immediatly. I have my strength back so long as I have a helping of junk food everyday. What is going on?

  29. Beautifully said. And I agree. Dr Hyman is a medical genius and his holistic approach is a welcome and desperately needed approach 🙂

  30. My family laughed when I told them I would bulk up with Max Muscle Method, but then I showed them the results. Go google Max Muscle Method to see their reaction.

  31. I'd like to learn how to get laid. My friend has started going out with a stunning gal basically because 60 days back he registered to a website named Master Attraction I'm jealous because I wish to fall madly in love as well. Why is it so difficult? I'm going to take a look at this Jake Ayres man's emails to find out if it might help somebody like me. Strange point is, my friend used to have Zero luck with females. How can you transform that swiftly? His girl's a fucking model.

  32. My midget nephew managed to make the hottest pole dancer I've ever seen fall for him as he used the Cupid Love System (search in Google). I wish I found myself pleased for him but I wish an elegant individual would fall for me. I'm exceptionally green with envy. Does that mean I'm a horrible individual?

  33.    He right on track,  but because of the easiness of the way many chose to ignore or  over look it. What he is saying make absolute sense!

  34. When results from drug trials are not hidden by the drug companies anymore (45% of the total number of drug studies), I'll trust evidence based medicine and conventional medicine. That's why sites like SBM are not convincing to many patients, including myself despite the huge wall of well written text. If you cherrypick the drug studies to get FDA approval, you're no more trustworthy than functional medicine. I don't completely trust the oncologists pushing expensive chemo drugs for big pharma just like I don't trust FM docs who push supplements. I'm not going to turn down 80% survival with chemo vs. 50% with no chemo, but my trust in science is gone. Money corrupts no matter who it is. In the end, we're down to anecdotes from real patients (not supplement pushers) because the scientific evidence is incomplete thanks to big pharma. There are a lot of anecdotes and positive n=1 results in my family with FM, so we will take the easy and cheap parts of FM (eg. gluten free diet).

  35. This guy has all of the traits of a pseudoscientist, talking about "imbalances" and "ultrawellness"… amazing how intelligent people can fool Google and the general public and scare them from vaccines etc… let alone fool enough people to become a trusted medical advisor to Bill and Hillary Clinton…

  36. I have been eating like the good Dr suggests for 3 months now , I have little or no white carbs , organic when ever i can , high proportion of protein and fat ( quality fats such as olive oil , nuts , seeds , avocados ) organic coffee with grass fed butter .

    I have lost 20lbs , have more energy then ever before , I can train harder than I could 30 years ago most impressive of all is improved memory , mood , concentration and each month i notice im still improving , I have tried most diets and ways of eating and just about every exercise method going this is the best by far it has changed my life 🙂 🙂 🙂

  37. This is glorious, I have been researching "how do you know if something is wrong with your thyroid" for a while now, and I think this has helped. Have you heard people talk about – Yannabarn Vanish Thyroid – (search on google ) ? Ive heard some extraordinary things about it and my mate got excellent success with it.

  38. Winner of a video, I have been researching "thyroid disease symptoms in young women" for a while now, and I think this has helped. Ever heard of – Yannabarn Vanish Thyroid – (should be on google have a look ) ? Ive heard some unbelievable things about it and my brother in law got cool results with it.

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