Patients and Providers Share Their Perspective on DUPIXENT® (dupilumab)
08
March

By Adem Lewis / in , , , , , , , , , , , , , , , , , , , , , , , /


If you are living with uncontrolled moderate-to-severe
atopic dermatitis and are curious about DUPIXENT, watch this video to hear how other patients
and a healthcare provider have discussed DUPIXENT as a treatment option. Please watch and carefully review the Important
Safety Information presented in this video and see the accompanying full Prescribing
Information including Patient Information. DUPIXENT is a prescription medicine used to
treat people 12 years of age and older with moderate-to-severe atopic dermatitis (eczema)
that is not well controlled with prescription therapies used on the skin (topical), or who
cannot use topical therapies. DUPIXENT can be used with or without topical
corticosteroids. It is not known if DUPIXENT is safe and effective
in children with atopic dermatitis under 12 years of age. [Music plays] When I first heard about DUPIXENT,
I was curious about what type of drug it would be and how it could help my skin.My doctor
did explain to me that DUPIXENT was a little different than other treatments, and he encouraged
me to do my own research and to be more involved with the decision-making process. I wanted to be involved in the decision-making
process because it’s my body and it’s my disease. I really was interested in doing
research about the medication. I wanted to know how it was going to work
with my body and my immune system. It was really important for me to find out
everything I could about DUPIXENT. When I started doing my research and talking
to doctors, my first thought was, “Is it going to work for me?” When people have tried a number of different
topical therapies and they’re just not doing well, that’s really where DUPIXENT falls. It’s for those patients who’ve really tried
in earnest but are still suffering, and that’s really the group that I’m focused on. I had tried, I think, just about everything
out there. I had done all the topical things. I had done phototherapy. And I was not getting results. So, when I started talking to my healthcare
team about DUPIXENT, I was hopeful. This was something that I thought could really
work for me. My doctor introduced DUPIXENT to me by telling
me that he had other patients taking it, and they had improvement in their conditions. I had a little reluctance to taking it, but
he was confident that it could help me. When I introduce DUPIXENT as a treatment for
patients, I first explain that it is not an immunosuppressant, because I think many patients
are afraid that a systemic medicine would suppress the entire immune system. I really emphasize that this is a treatment
that’s going to cool down the inflammation both in the skin and in the rest of the body
to help get them some relief. I learned that DUPIXENT was not a topical
or a oral medication. This drug works with my body to help reduce
underlying inflammation and potentially clear my skin. That was probably the most exciting thing
that I found out about DUPIXENT, because I always knew that I needed something that was
going to work from the inside-out. I did have a lot of questions for my dermatologist. You know, I asked her, “Have you used this
medication, how well has it worked, what kind of results have you seen?” A question I often get about DUPIXENT is,
“How much could it help me?” And that’s somewhat difficult to answer because,
of course, each patient is different. I usually tell them very frankly that I have
seen a good amount of success in patients just like them, moderate-to-severe atopic
dermatitis that’s uncontrolled. I tell them that DUPIXENT is, unfortunately,
not a cure. They’re still going to have to be careful. It’s not going to solve all their problems. But it’s an important tool in our toolbox
that may get them better. My doctor told me that other patients had
seen success. He specifically told me that I could experience
the same, but he did say it varies from patient to patient. My dermatologist discussed with me that it
may take several weeks or potentially months to see improvement in my skin. You know, a few weeks may seem like a long
time to some people, but when you’ve lived with a condition for years, you know, a few
weeks is fast. DUPIXENT is a systemic medication, and so
it’s important to share the safety information with the patient. I talk to my patients about the risk of serious
side effects like allergic reactions or eye problems and what to look out for if these
were to occur. I also talk about some of the common side
effects like injection site reaction, eye and eyelid inflammation, including the redness,
swelling and itching that’s sometimes seen, and cold sores in the mouth or on the lips. I also introduce the idea that it’s an injectable
medication, which may be different than things they’ve tried in the past. When I first heard that I had to inject it,
I had some hesitations. I, for some reason, I just felt like this
was a little bit out of my comfort zone. I’ve never really been a big fan of needles
myself. I went “No way.” (Laughs) There are a number of things that
we do to help people get over the fear or concerns with self-injection. The first thing is that for the loading dose,
that initial dose that we have to give before you begin your every two-week treatment, we
actually encourage the patients to come into the office. And, usually, I’ll do the first shot. I’ll demonstrate it for them, and I’ll show
them what I do. And then there’s a second syringe for the
loading. I’ll let them do that to themselves under
my guidance. Another thing is to enroll them in the DUPIXENT
MyWay program, where a nurse can actually help them with some of those issues around
the self-injection process. My doctor wanted me to feel good about taking
it, so he suggested that I could come to him for the first few injections until I was comfortable
actually doing it myself, and that definitely put me at ease. When I started talking to the health care
team about doing the injection, they shared with me that my husband could be trained on
it, too, and that he could give me the injection. That really helped calm me, because I thought
in the beginning that might be a good thing to try if I couldn’t do it. My dermatologist explained the process. She explained that it would be something that
I should be able to become comfortable with. People with atopic dermatitis, we have to
overcome things almost daily. So, for me, it was just another challenge
that I would have to overcome. After a lot of research and careful consideration
and realizing how important it is for my condition, my doctor and I decided to move forward with
taking DUPIXENT. Finally, you know, with my primary doctor
and my dermatologist, I made the decision to pursue treatment with DUPIXENT. I explored everything, talked to my doctors
a lot about it, and asked every question I could and decided that
it was the right thing for me.


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