100 thoughts on “Salbutamol and Asthma – Periodic Table of Videos

  1. Nice it saved my life quite a few times now 🙂

    Is there any cortisone in that spray? I know theres alcohol in there cause its written on it

  2. Reminds me of diabetes. A serious condition, however with the appropriate treatment its near enough harmless.

  3. i just had mini asthma attack before watching this xD so i was inhaling salbutamol a sec ago i heart salbutamol without it i'd probably been dead years ago since i was born with asthma an as a child i would have massive attacks that could have easily killed me if it werent for hospitals

  4. Cool. so Ventolin (salbutamol) is basically a type of Adrenalin that lasts longer, and is customised for just one type of receptor in your lungs.

    I never knew it was Adrenalin! I've been taking it all my life haha.

  5. @7point2 we have trouble with both.

    the lungs don't suddenly constrict when we have to breath out, and then happy de-constrict when breathing in. No

  6. @TheBrownGeorge i'm asthmatic and my doctor told me to take it before i exercise coz it's like a steroid, haha he's such a cheater.

    fuck i wonder if he cheated on his doctor exams

  7. @kamakazechris no man. no.

    Diabetes (type1) sucks balls. You have to measure out the amount of insulin you inject yourself depending on so many factors, and overdoses are so common they are expected.

    Asthma you just huff on a stick whenever you feel like you need it.

  8. you really need to get this guy to do way more videos, he is soo interesting and the video does not get boring even for a second. please consider this as there are so many drugs to talk about.

  9. Salbutamol is what I use. I don't have to use it every day as my astma isn't that severe, but it really helps when a heavy attack happens. Having the feeling that you're choking is very bad, Salbutamol gets rid of it very quick. Thank you for the video!

  10. I can just see some pharmaceutical company trying to sue this channel for educating people on the compounds involved under the guise of "dispersing corporate secrets"…

  11. Interestingly enough I just saw a video that a UCLA professor made after conducting experiments with marijuana.In it he explains some baffling results, one of them being that when users consumed marijuana their airwaves would actually dilate instead of constricting like when smoking cigarettes. I've actually heard of people that are prescribed medical marijuana for asthma in California.What are your thoughts on it?

  12. @flakemusic86 Well, generally, they (the industry) don't add another group to the molecule which has the basic principle. Instead, like the case of salbutamol, the synthesis starts with a molecule which barely resembles noradrenaline. You can find the chain of reactions at wikipedia.

  13. @flakemusic86 It's called rational drug design. Chemists take a starter molecule, known as a lead ("leed") compound and change it so that it can produce the best effect. The lead compound can be an endogenous compound already found in the body and changed to produce a stronger or longer lasting effect, like with salbutamol, or can be a compound extracted from a plant etc. There is a loose set of rules about what groups to add to change the effects of the drug but it's too much to go into here!

  14. @Enejac marijuana may beat salbutamol for you, but for other people the efficacy may be different.
    Also getting high everytime you want to breathe better can sometimes be inconvenient.

    What may be the best for you, is not necessarily the best for everyone. For other people salbutamol may work better.

  15. Fantastic! I use this drug very so often, and I always wondered in what ways does it relieves the asthma symptoms. Thank you for the plain-words explanations.

  16. @flakemusic86 if that sort of thing interests you, I think you would really enjoy some upper level chemistry classes such as organic chemistry and later on biochemistry! It will explain all the processes in painstaking detail 🙂

  17. Excellent excellent video, the explanation was nice short and simple and made tons on sense. Great job guys!

  18. @punkapie95 Historically many different people discovered the same compound and named it different names, there have also in the past been several standardized naming systems that have since been abandoned, and sometimes the names just stick. Hope this helped.
    the current "proper" name is "(R)-4-(1-hydroxy-
    2-(methylamino)ethyl)benzene-1,2-diol", ill stick with adrenaline!

  19. @TheScienceiscool That's really interesting, especially since I'll be taking AP Chemistry next year. Thanks a lot!

  20. @flakemusic86 Take an organic chemistry class with a lab component. You'll spend the who second semester doing synthesis reactions and understanding mechanisms. If you don't have the time, just buy the book "Pushing Electrons" it'll give you the basics for molecular mechanisms.

  21. Dr. Stockman says on 3:342 that it doesn't act on the heart. He obviously never used an inhaler (the blue one, it's called Ventolin here) because when you use this too much, your heart rate goes through the roof. I've had this happen to me on a couple of occasions when I used my inhaler too much. Still an interesting video.

  22. @Muscleduck On the few occasions I've used this I found I get a dose-proportional increase in heartrate of 10-15bpm per 200mg. The most I've ever taken was 600mg in a day and I got flushing, nausea and so much anxiety I thought I was going to die…

  23. Excelente! Tenho asma desde bebê! Acho que ainda tenho, mas tomei muuuuito salbutamol! Sentia-me realmente aliviada, agora conhecendo o mecanismo de ação, atrelando aos meus conhecimentos adquiridos com faculdade de Química, fico bem feliz!

  24. Ok so in asthma we see bronchoconstriction and a hugely successful theraputic solution comes in the form of salbutamol, a beta2 adrenoceptor agonist, but what is its mechanism of action by which it causes airway smooth muscle cells to relax?

  25. @davidsweeney111: It's pretty complicated. Basically, activation of a Beta 2 receptor activates G-proteins in the cell membrane. G-proteins activate a trans-membrane protein called adenylate cyclase. Adenylate cyclase catalyses the conversion of ATP into cAMP and through additional pathways, cAMP causes bronchodilation. Collectively, this is commonly referred to as a G-protein linked signaling cascade.

  26. hi, I am studying naturopathy and aromatherapy. Is that really true that we can make something natural with plants to replace this synthetic salbutamol?

  27. No. Because everything "Natural" in the plants is the same thing as something "artificially" made. There is no such thing as "Natural" because it's still a chemical.

  28. Yeah, I'm big on being natural, I used to have eight children but every few years I would make them outrun a lion until they where whittled down to two as nature intended. Right now, I have a cold sweat and have lost massive amounts of weight because a parasitic bug is burrowing into the bas of my spine as nature intended. Oh crap its started raining, and I still haven't patched the roof of my mud hut. Are mud huts natural? Maybe I should be trying to sleep in a mud ditch as nature intended.

  29. Not sure if I am the first to tell you, however naturopathy is actually a pseudo science and does not help anyone at all. If you want to actually help people, make sure the method you choose to do it actually works and is proven to work, has sustained rigorous peer evaluations, can be experimentally proven, and has actual evidence to booster its findings. By attempting to help people with things that do not work, you place them in harm by not giving them the treatment they actually need.

  30. Nice video. I think the structures of adrenaline and noradrenaline are the wrong way round though. Adrenaline has an N-methyl, noradrenaline does not.

  31. I know a lot of people wont like this. I foresee a world where everyone has to be treated for this and diabetes and what ever other mutations. Because humans feel the need to support the life of people with bad genes enabling them to rinse the bad genes with the good ones. Eventually there will be no normal people as we see normal today.
    Having said that, If I had asthma Id use it. I would not just die. But id feel bad if I mixed my genes with someone who does not have it.
    Dont undo evolution

  32. at 3.51 Dr. Stockman explains why Salbutamol doesn't pass the blood brain barrier.  If it did, than it would most likely become a stimulant of some variation. 

  33. I was forced to run cross country events at school by moronic sports teachers in the late 1950s and early 1960s and nearly died of asthma on at least one occasion as a result (until my father bloodied one or two of their noses and I was allowed to study instead). Salbutamol has changed my life since then and continues to do so. Oh, and I became a science teacher, instead of a corpse in a copse somewhere. And sports teachers mostly remain overpaid morons.

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