At the moment we don’t have one registry of people with severe asthma. So first off we don’t know how many people there are categorically with severe asthma. We only have a sense and an understanding through population studies that we think there are about 200 to 250 thousand people but we don’t know for sure. We also don’t know yet what type of asthma they have within that because we haven’t understood it. So by registering people into a registry you can then see that you can understand more about those individuals, and it will help us understand severe asthma more. It will help us inform which treatments are best for which groups, and and make sure that we are understanding the impact of those treatments too.